Is Botox Safe for People Over the Age of 65?

Is Botox Safe for People Over the Age of 65?

Posted on December 31, 2025 by Dr Eleonora Fedonenko

The FDA has officially approved Botox for a limited number of uses, and for adults up to the age of 65. However, this does not mean that its use outside these limits is unsafe or illegal. Botox is used for a very large number of “off-label” uses, even though these uses are also not officially sanctioned. So, what does it mean to use Botox off-label, and does the FDA’s age limit mean that its use is unsafe for those over 65?

What Does Off-Label Actually Mean?

The FDA has tested only a relatively small range of Botox uses, and when it gives its official approval, it is always done in extremely limited and specific circumstances. However, this does not mean that other uses are unsafe; it simply means that they have not been investigated with the same rigor. In fact, the vast majority of Botox procedures performed today are not officially approved, and they are perfectly safe when performed within recognized boundaries.

The FDA’s 65 age limit means that there were very few individuals older than 65 in their test groups, not that they determined that treating older individuals would be dangerous. The FDA does not prohibit the use of Botox in these patients.

Potential Challenges or Side Effects for Older Patients Who Receive Botox Injections

A significant number of Botox procedures have been performed on older patients, and there are generally no differences in how older patients react to the procedure compared to younger ones.

Older patients are, of course, more likely to have developed a larger range of skin problems simply by virtue of having lived longer. Their skin is more likely to have suffered sun-related damage, they’re more likely to have low levels of collagen and elastin, reduced fat deposits, and their skin is probably thinner than it was in their youth. The cumulative effects of aging often mean that

Botox treatments are somewhat less likely to give complete relief from lines and wrinkles. The procedure will result in cosmetic improvements, but patients with unreasonable expectations could be disappointed. Of course, this caveat also applies to younger patients.

Older patients are somewhat more likely to develop temporary side effects, such as bruising or swelling. As in younger patients, these are generally mild and short-lived.

How Practitioners Adapt Botox for Older Adults

Skillful and experienced practitioners often adapt their Botox treatments for older patients, the same way they would adapt their treatment protocols for any patient who presents special circumstances. This is part and parcel of how professionals adapt every procedure to the patient’s needs, rather than simply applying a cookie-cutter solution to everyone they see.

It’s common for practitioners to use lower doses of Botox and distribute them more widely to compensate for age-related changes in muscle density and skin resilience. Providers who offer a range of non-invasive cosmetic procedures have a number of other treatment options available, in particular, dermal fillers. These procedures are often combined with Botox and can compensate for a lack of volume and complement the use of Botox.

Other Factors Influencing Botox Treatments for People Over the Age of 65

Some providers may be less willing to perform some procedures on older patients. As an example, shrinking the volume of the masseter muscles involves more trade-offs with older patients. Reducing muscle mass can have unintended consequences, such as increasing the risk of skin folds around the jowls. A skillful practitioner always has to perform a careful balancing act between treating some problems and possibly creating others. Older patients are not unique in this respect, but they may present more challenges than do younger patients.

As with all cosmetic procedures, you will increase your chances of good results by looking for a skilled practitioner who can demonstrate years of experience and who is willing to take the time to tailor their treatments to every patient’s individual needs.

The good news is that Botox remains a valid option for those over 65, and can provide a reliable way to soften dynamic lines and wrinkles, and to improve their appearance and self-confidence.

Schedule Your Personalized Botox Consultation Today with Your Laser Skin Care

Your Laser Skin Care practitioners are medically qualified, with extensive experience performing Botox procedures. We tailor all treatments to each patient’s needs and prioritize minimalist application and natural-looking results. We invite you to contact us for more information on this or any of the other non-invasive cosmetic procedures we offer. We can help you choose the safest, most effective, and most cost-effective way to achieve your cosmetic goals. Call us at (323) 525-1516 to schedule a free consultation, or visit us online for more information.

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Meet Dr. Fedonenko

Dr. Eleonora Fedonenko is a member of the American College of Physicians and is Board Certified in Internal Medicine.

She completed her Residency at the University of Virginia School of Medicine in 1998 and has since specialized in Cosmetic Dermatology.

She obtained additional training in aesthetic medicine procedures soon thereafter, and the results of her extensive training and experience show in each and every patient’s face. She’s a doctor that can truly been trusted with your skin care and anti-aging needs.

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